HPOB

Catalog No. A14197

HPOB是组蛋白去乙酰化酶6(HDAC6；IC50 = 56 nM)。

Technical details

Catalog Num	A14197
M. Wt	314.3
Formula	C17H18N2O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1429651-50-2
Synonyms	0
SMILES	C1=CC=C(C=C1)N(CCO)C(=O)CC2=CC=C(C=C2)C(=O)NO

Biological Activity

HPOB是组蛋白去乙酰化酶6(HDAC6；IC50 = 56 nM)。

Targets

Target	Value
HDAC6	IC50: 56nM
HDAC3	IC50: 1.7μM
HDAC8	IC50: 2.8μM
HDAC1	IC50: 2.9μM
HDAC10	IC50: 3.0μM
HDAC2	IC50: 4.4μM
HDAC4	IC50: >10μM
HDAC5	IC50: >10μM
HDAC7	IC50: >10μM
HDAC9	IC50: >10μM
HDAC11	IC50: >10μM

Solubility *

In vitro	DMSO	60 mg/mL (190.87 mM)
	Water	Insoluble
	Ethanol	Warmed: 37 mg/mL (117.7 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.82 mL	159.08 mL	318.17 mL
0.5 mM	6.36 mL	31.82 mL	63.63 mL
1 mM	3.18 mL	15.91 mL	31.82 mL
5 mM	0.64 mL	3.18 mL	6.36 mL

*The above data is based on the productmolecular weight 314.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.