ME0328
Catalog No. A14309
ME0328是一种有效的选择性PARP抑制剂,对PARP3的IC50为0.89μM,选择性是PARP1的7倍。
Catalog Num | A14309 |
---|---|
M. Wt | 321.37 |
Formula | C19H19N3O2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1445251-22-8 |
Synonyms | ME 0328 |
SMILES | C[C@@H](C1=CC=CC=C1)NC(=O)CCC2=NC(=O)C3=CC=CC=C3N2 |
ME0328是一种有效的选择性PARP抑制剂,对PARP3的IC50为0.89μM,选择性是PARP1的7倍。
Targets
PARP3 | PARP1 | |||
0.89 μM | 6.3 μM |
In vitro | DMSO | 60 mg/mL (186.69 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 31.12 mL | 155.58 mL | 311.17 mL |
0.5 mM | 6.22 mL | 31.12 mL | 62.23 mL |
1 mM | 3.11 mL | 15.56 mL | 31.12 mL |
5 mM | 0.62 mL | 3.11 mL | 6.22 mL |
*The above data is based on the productmolecular weight 321.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.