WZ4003
Catalog No. A14312
WZ4003是一种高度特异性的NUAK激酶抑制剂,对于NUAK1和NUAK2的IC50为20 nM和100 nM。
Catalog Num | A14312 |
---|---|
M. Wt | 496.99 |
Formula | C25H29ClN6O3 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1214265-58-3 |
Synonyms | WZ 4003, WZ-4003 |
SMILES | CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC |
WZ4003是一种高度特异性的NUAK激酶抑制剂,对于NUAK1和NUAK2的IC50为20 nM和100 nM。
Targets
NUAK1 (Cell-free assay) | NUAK2 (Cell-free assay) | |||
20 nM | 100 nM |
In vitro | DMSO | 7 mg/mL (14.08 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.12 mL | 100.61 mL | 201.21 mL |
0.5 mM | 4.02 mL | 20.12 mL | 40.24 mL |
1 mM | 2.01 mL | 10.06 mL | 20.12 mL |
5 mM | 0.4 mL | 2.01 mL | 4.02 mL |
*The above data is based on the productmolecular weight 496.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.