Ro 48-8071 fumarate
Catalog No. A14321
Ro 48-8071 fumarate在2,3-氧化角鲨烯环化酶（OSC）的水平上抑制胆固醇的生物合成。它可以在纳摩尔级的HepG2细胞中阻断OSC和胆固醇的合成。新型降脂剂。
| Catalog Num | A14321 |
|---|---|
| M. Wt | 564.4 |
| Formula | C23H27NO2BrF.C4H4O4 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 189197-69-1 |
| Synonyms | Ro 488071, Ro488071 |
| SMILES | CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C.C(=C/C(=O)O)\C(=O)O |
Ro 48-8071 fumarate在2,3-氧化角鲨烯环化酶（OSC）的水平上抑制胆固醇的生物合成。它可以在纳摩尔级的HepG2细胞中阻断OSC和胆固醇的合成。新型降脂剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.72 mL | 88.59 mL | 177.18 mL |
| 0.5 mM | 3.54 mL | 17.72 mL | 35.44 mL |
| 1 mM | 1.77 mL | 8.86 mL | 17.72 mL |
| 5 mM | 0.35 mL | 1.77 mL | 3.54 mL |
*The above data is based on the productmolecular weight 564.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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