LMK-235

Catalog No. A14341

LMK-235是选择性组蛋白脱乙酰基酶(HDAC) 4和HDAC5抑制剂。

Technical details

Catalog Num	A14341
M. Wt	294.35
Formula	C15H22N2O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1418033-25-6
Synonyms	LMK235, LMK 235
SMILES	CC1=CC(=CC(=C1)C(=O)NOCCCCCC(=O)NO)C

Biological Activity

LMK-235是选择性组蛋白脱乙酰基酶(HDAC) 4和HDAC5抑制剂。

Targets

HDAC5	HDAC4
4.2 nM	11.9 nM

Solubility *

In vitro (25°C)	DMSO	50 mg/mL (169.86 mM)
	Water	Insoluble
	Ethanol	50 mg/mL (169.86 mM)
In vivo	5%DMSO+30%PEG300+5%TW80+ddH2O	12 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.97 mL	169.87 mL	339.73 mL
0.5 mM	6.79 mL	33.97 mL	67.95 mL
1 mM	3.4 mL	16.99 mL	33.97 mL
5 mM	0.68 mL	3.4 mL	6.79 mL

*The above data is based on the productmolecular weight 294.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.