PI-103 Hydrochloride

Catalog No. A15212

PI-103 Hydrochloride是对重组PI3K亚型p110alpha(IC50 = 2 nM),p110beta(IC50 = 3 nM),p110delta(IC50 = 3 nM)和p110gamma(IC50 = 15 nM)具有低IC50值的有效抑制剂,对mTOR的效力较低/DNA-PK,IC50为30 nM/23 nM。
Catalog Num A15212
M. Wt 384.82
Formula C19H17ClN4O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 371935-79-4
Synonyms PI 103 hydrochloride, PI103 hydrochloride
SMILES C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl
PI-103 Hydrochloride是对重组PI3K亚型p110alpha(IC50 = 2 nM),p110beta(IC50 = 3 nM),p110delta(IC50 = 3 nM)和p110gamma(IC50 = 15 nM)具有低IC50值的有效抑制剂,对mTOR的效力较低/DNA-PK,IC50为30 nM/23 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.99 mL 129.93 mL 259.86 mL
0.5 mM 5.2 mL 25.99 mL 51.97 mL
1 mM 2.6 mL 12.99 mL 25.99 mL
5 mM 0.52 mL 2.6 mL 5.2 mL

*The above data is based on the productmolecular weight 384.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.