Acetyl-Calpastatin (184-210) (human)

Catalog No. A15290

Acetyl-Calpastatin (184-210) (human)选择性钙蛋白酶抑制剂。强烈抑制钙蛋白酶I（Ki = 0.2 nM）和II，但不抑制木瓜蛋白酶，胰蛋白酶和组织蛋白酶L（Ki = 6 uM）。增加淀粉样β蛋白（Aβ）42，Aβ40和Aβ42比率的分泌。

Technical details

Catalog Num	A15290
M. Wt	3177.65
Formula	C142H230N36O44S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	123714-50-1
Synonyms
SMILES	CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	3.15 mL	15.73 mL	31.47 mL
0.5 mM	0.63 mL	3.15 mL	6.29 mL
1 mM	0.31 mL	1.57 mL	3.15 mL
5 mM	0.06 mL	0.31 mL	0.63 mL

*The above data is based on the productmolecular weight 3177.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Acetyl-Calpastatin (184-210) (human)

Technical details

Biological Activity

Preparing Stock Solutions