SW033291
Catalog No. A15798
SW033291是15-PGDH的小分子抑制剂(Ki = 0.1 nM),可增加骨髓和其他组织中前列腺素PGE2的水平。
Catalog Num | A15798 |
---|---|
M. Wt | 412.59 |
Formula | C21H20N2OS3 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 459147-39-8 |
Synonyms | SW 033291, SW-033291 |
SMILES | NC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21 |
SW033291是15-PGDH的小分子抑制剂(Ki = 0.1 nM),可增加骨髓和其他组织中前列腺素PGE2的水平。
Targets
15-PGDH | 15-PGDH | |||
0.1 nM(Ki) | 1.5 nM |
In vitro (25°C) | DMSO | 77 mg/mL (186.62 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 30 mg/mL (72.7 mM) | ||
In vivo | 5% DMSO+corn oil | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.24 mL | 121.19 mL | 242.37 mL |
0.5 mM | 4.85 mL | 24.24 mL | 48.47 mL |
1 mM | 2.42 mL | 12.12 mL | 24.24 mL |
5 mM | 0.48 mL | 2.42 mL | 4.85 mL |
*The above data is based on the productmolecular weight 412.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.