7ACC1

Catalog No. A15810

7ACC1在富含乳酸的肿瘤微环境中选择性干扰乳酸通量；在表达MCT1和MCT4转运蛋白的肿瘤细胞中，乳酸抑制乳酸盐流入，但不流出。

Product Citations

Daniel Gundel, .et al. Preclinical Evaluation of [18F]FACH in Healthy Mice and Piglets: An 18F-Labeled Ligand for Imaging of Monocarboxylate Transporters with PET, Int J Mol Sci, 2021, Feb; 22(4): 1645 PMID: 33562048

Technical details

Catalog Num	A15810
M. Wt	261.27
Formula	C14H15NO4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	50995-74-9
Synonyms	DEAC, Coumarin D 1421, D 1421
SMILES	CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)O

Biological Activity

7ACC1在富含乳酸的肿瘤微环境中选择性干扰乳酸通量；在表达MCT1和MCT4转运蛋白的肿瘤细胞中，乳酸抑制乳酸盐流入，但不流出。

Solubility *

In vitro	DMSO	45 mg/mL (172.23 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.27 mL	191.37 mL	382.75 mL
0.5 mM	7.65 mL	38.27 mL	76.55 mL
1 mM	3.83 mL	19.14 mL	38.27 mL
5 mM	0.77 mL	3.83 mL	7.65 mL

*The above data is based on the productmolecular weight 261.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.