GSK1016790A

Catalog No. A15854

GSK1016790A是一种新型有效的TRPV4激活剂（瞬态受体电位香草酸4），在脉络丛上皮细胞中的EC50为34nM。

Technical details

Catalog Num	A15854
M. Wt	655.61
Formula	C28H32Cl2N4O6S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	942206-85-1
Synonyms	GSK101
SMILES	CC(C)CC(C(=O)N1CCN(CC1)C(=O)C(CO)NS(=O)(=O)C2=C(C=C(C=C2)Cl)Cl)NC(=O)C3=CC4=CC=CC=C4S3

Biological Activity

GSK1016790A是一种新型有效的TRPV4激活剂（瞬态受体电位香草酸4），在脉络丛上皮细胞中的EC50为34nM。

Targets

TRPV4

Solubility *

In vitro	DMSO	98 mg/mL (149.47 mM)
	Water	Insoluble
	Ethanol	98 mg/mL (149.47 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.25 mL	76.26 mL	152.53 mL
0.5 mM	3.05 mL	15.25 mL	30.51 mL
1 mM	1.53 mL	7.63 mL	15.25 mL
5 mM	0.31 mL	1.53 mL	3.05 mL

*The above data is based on the productmolecular weight 655.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.