AG-18 (Tyrphostin 23)

Catalog No. A15940

AG-18 (Tyrphostin 23)是人表皮癌细胞系A431中的表皮生长因子（EGF）受体激酶抑制剂，IC50值为35M。

Technical details

Catalog Num	A15940
M. Wt	186.17
Formula	C10H6N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	118409-57-7
Synonyms	RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin A23, Tyrphostin AG-18
SMILES	N#C/C(C#N)=C/C1=CC=C(O)C(O)=C1

Biological Activity

AG-18 (Tyrphostin 23)是人表皮癌细胞系A431中的表皮生长因子（EGF）受体激酶抑制剂，IC50值为35M。

Targets

EGFR
35 μM

Solubility *

In vitro	DMSO	34 mg/mL (182.63 mM)
	Water	Insoluble
	Ethanol	34 mg/mL (182.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	53.71 mL	268.57 mL	537.14 mL
0.5 mM	10.74 mL	53.71 mL	107.43 mL
1 mM	5.37 mL	26.86 mL	53.71 mL
5 mM	1.07 mL	5.37 mL	10.74 mL

*The above data is based on the productmolecular weight 186.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.