HI TOPK 032
Catalog No. A16042
HI-TOPK-032是一种有效的选择性TOPK抑制剂。在体外,HI-TOPK-032强烈抑制TOPK激酶活性,但对细胞外信号调节激酶1(ERK1),c-jun-NH2-激酶1或p38激酶活性影响很小。
Catalog Num | A16042 |
---|---|
M. Wt | 369.4 |
Formula | C20H11N5OS |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 487020-03-1 |
Synonyms | HI-TOPK-032, HI-TOPK032, HI-TOPK 032 |
SMILES | O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2 |
HI-TOPK-032是一种有效的选择性TOPK抑制剂。在体外,HI-TOPK-032强烈抑制TOPK激酶活性,但对细胞外信号调节激酶1(ERK1),c-jun-NH2-激酶1或p38激酶活性影响很小。
In vitro | DMSO | 4 mg/mL (10.82 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.07 mL | 135.35 mL | 270.71 mL |
0.5 mM | 5.41 mL | 27.07 mL | 54.14 mL |
1 mM | 2.71 mL | 13.54 mL | 27.07 mL |
5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
*The above data is based on the productmolecular weight 369.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.