HI TOPK 032

Catalog No. A16042

HI-TOPK-032是一种有效的选择性TOPK抑制剂。在体外,HI-TOPK-032强烈抑制TOPK激酶活性,但对细胞外信号调节激酶1(ERK1),c-jun-NH2-激酶1或p38激酶活性影响很小。
Catalog Num A16042
M. Wt 369.4
Formula C20H11N5OS
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 487020-03-1
Synonyms HI-TOPK-032, HI-TOPK032, HI-TOPK 032
SMILES O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2
HI-TOPK-032是一种有效的选择性TOPK抑制剂。在体外,HI-TOPK-032强烈抑制TOPK激酶活性,但对细胞外信号调节激酶1(ERK1),c-jun-NH2-激酶1或p38激酶活性影响很小。
In vitro DMSO 4 mg/mL (10.82 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.35 mL 270.71 mL
0.5 mM 5.41 mL 27.07 mL 54.14 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.