LDN-214117

Catalog No. A16096

LDN-214117是一种选择性有效的ALK2抑制剂。LDN-214117对ALK2的抑制最大，生化IC50为24 nM。

Technical details

Catalog Num	A16096
M. Wt	419.52
Formula	C25H29N3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1627503-67-6
Synonyms	LDN214117, LDN 214117
SMILES	COC1=C(OC)C(OC)=CC(C2=C(C)N=CC(C3=CC=C(N4CCNCC4)C=C3)=C2)=C1

Biological Activity

LDN-214117是一种选择性有效的ALK2抑制剂。LDN-214117对ALK2的抑制最大，生化IC50为24 nM。

Targets

ALK2
24 nM

Solubility *

In vitro (25°C)	DMSO	74 mg/mL (176.39 mM)
	Water	Insoluble
	Ethanol	74 mg/mL (176.39 mM)
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.84 mL	119.18 mL	238.37 mL
0.5 mM	4.77 mL	23.84 mL	47.67 mL
1 mM	2.38 mL	11.92 mL	23.84 mL
5 mM	0.48 mL	2.38 mL	4.77 mL

*The above data is based on the productmolecular weight 419.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.