7,8-Dihydroxyflavone

Catalog No. A16123

7,8-Dihydroxyflavone是一种选择性的酪氨酸激酶受体B（神经营养因子/原肌球蛋白受体激酶B；TrkB）激动剂，可用于帮助识别和区分由TrkB激活介导的生理效应和细胞信号通路。涉及神经保护，记忆，血管舒张和高血压。

Technical details

Catalog Num	A16123
M. Wt	254.24
Formula	C15H10O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	38183-03-8
Synonyms	7,8-DHF
SMILES	OC1=C(C2=CC=C1O)OC(C3=CC=CC=C3)=CC2=O

Biological Activity

Targets

TrkB receptor
320 nM(Kd)

Solubility *

In vitro	DMSO	44 mg/mL (173.06 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (3.93 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	39.33 mL	196.66 mL	393.33 mL
0.5 mM	7.87 mL	39.33 mL	78.67 mL
1 mM	3.93 mL	19.67 mL	39.33 mL
5 mM	0.79 mL	3.93 mL	7.87 mL

*The above data is based on the productmolecular weight 254.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.