IKK epsilon-IN-1

Catalog No. A16298

IKK epsilon-IN-1是有效的IKKε抑制剂；抑制IRF3的原位IKKε介导的磷酸化，IC50值小于约100 nM。

Technical details

Catalog Num	A16298
M. Wt	457.52
Formula	C26H27N5O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1292310-49-6
Synonyms
SMILES	C1COCCC1OC2=C(C=C(C=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5)C#N

Biological Activity

IKK epsilon-IN-1是有效的IKKε抑制剂；抑制IRF3的原位IKKε介导的磷酸化，IC50值小于约100 nM。

Solubility *

In vitro	DMSO	57 mg/mL (124.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.86 mL	109.28 mL	218.57 mL
0.5 mM	4.37 mL	21.86 mL	43.71 mL
1 mM	2.19 mL	10.93 mL	21.86 mL
5 mM	0.44 mL	2.19 mL	4.37 mL

*The above data is based on the productmolecular weight 457.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

IKK epsilon-IN-1

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions