KPT276

Catalog No. A16341

KPT276是KPT-185的类似物，是核出口（SINE）和CRM1的选择性抑制剂。

Technical details

Catalog Num	A16341
M. Wt	426.26
Formula	C16H10F8N4O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1421919-75-6
Synonyms	KPT-276, KPT 276
SMILES	C1C(CN1C(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)(F)F

Biological Activity

KPT276是KPT-185的类似物，是核出口（SINE）和CRM1的选择性抑制剂。

Solubility *

In vitro (25°C)	DMSO	17 mg/mL (39.87 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.46 mL	117.3 mL	234.6 mL
0.5 mM	4.69 mL	23.46 mL	46.92 mL
1 mM	2.35 mL	11.73 mL	23.46 mL
5 mM	0.47 mL	2.35 mL	4.69 mL

*The above data is based on the productmolecular weight 426.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

KPT276

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions