4-Methylumbelliferone (4-MU)

Catalog No. A10015

4-Methylumbelliferone是透明质酸（HA）合成的选择性抑制剂，IC50为0.4 mM。被认为可通过消耗HA合成的常用底物UDP-葡萄糖醛酸来起抑制剂的作用。

Technical details

Catalog Num	A10015
M. Wt	176.2
Formula	C10H8O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	90-33-5
Synonyms	4-MU
SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)O

Biological Activity

4-Methylumbelliferone是透明质酸（HA）合成的选择性抑制剂，IC50为0.4 mM。被认为可通过消耗HA合成的常用底物UDP-葡萄糖醛酸来起抑制剂的作用。

Targets

Solubility *

In vitro	DMSO	30 mg/mL (170.29 mM)
	Water	Insoluble
	Ethanol	30 mg/mL (170.29 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	56.75 mL	283.77 mL	567.54 mL
0.5 mM	11.35 mL	56.75 mL	113.51 mL
1 mM	5.68 mL	28.38 mL	56.75 mL
5 mM	1.14 mL	5.68 mL	11.35 mL

*The above data is based on the productmolecular weight 176.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.