Amorolfine HCl

Catalog No. A10072

Amorolfine hydrochloride是一种吗啉类抗真菌药,可抑制D14还原酶和D7-D8异构酶,这些酶消耗麦角固醇并导致木质甾醇在真菌细胞质细胞膜中积聚。
Catalog Num A10072
M. Wt 354.0
Formula C21H36ClNO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 78613-38-4
Synonyms Amorolfin, Curanail, Loceryl, Locetar, Odenil
SMILES CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@H](O[C@H](C2)C)C.Cl
Amorolfine hydrochloride是一种吗啉类抗真菌药,可抑制D14还原酶和D7-D8异构酶,这些酶消耗麦角固醇并导致木质甾醇在真菌细胞质细胞膜中积聚。
In vitro DMSO 25 mg/mL (70.63 mM)
Water 8 mg/mL (22.6 mM)
Ethanol 64 mg/mL (180.8 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.25 mL 141.24 mL 282.49 mL
0.5 mM 5.65 mL 28.25 mL 56.5 mL
1 mM 2.82 mL 14.12 mL 28.25 mL
5 mM 0.56 mL 2.82 mL 5.65 mL

*The above data is based on the productmolecular weight 354.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.