Anastrozole

Catalog No. A10075

Anastrozole是第三代非甾体选择性芳香化酶抑制剂。与其他芳香酶抑制剂相比，它可能具有更高的选择性，没有任何内在的内分泌作用，并且对肾上腺类固醇的合成也没有明显的作用。

Technical details

Catalog Num	A10075
M. Wt	293.4
Formula	C17H19N5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	120511-73-1
Synonyms	Arimidex
SMILES	CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N

Biological Activity

Targets

Aromatase
15 nM

Solubility *

In vitro	DMSO	57 mg/mL (194.29 mM)
	Water	Insoluble
	Ethanol	57 mg/mL (194.29 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	34.08 mL	170.42 mL	340.83 mL
0.5 mM	6.82 mL	34.08 mL	68.17 mL
1 mM	3.41 mL	17.04 mL	34.08 mL
5 mM	0.68 mL	3.41 mL	6.82 mL

*The above data is based on the productmolecular weight 293.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.