AS703026 (Pimasertib)

Catalog No. A10089

AS703026 (Pimasertib)是一种新型的，选择性的，口服可生物利用的MEK1/2抑制剂，可抑制MM细胞的生长和存活以及细胞因子诱导的破骨细胞分化。

Technical details

Catalog Num	A10089
M. Wt	431.2
Formula	C15H15FIN3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1236699-92-5
Synonyms	AS-703026, MSC1936369B
SMILES	C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O

Biological Activity

AS703026 (Pimasertib)是一种新型的，选择性的，口服可生物利用的MEK1/2抑制剂，可抑制MM细胞的生长和存活以及细胞因子诱导的破骨细胞分化。

Solubility *

In vitro (25°C)	DMSO	78 mg/mL (180.89 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC+0.25% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.19 mL	115.96 mL	231.91 mL
0.5 mM	4.64 mL	23.19 mL	46.38 mL
1 mM	2.32 mL	11.6 mL	23.19 mL
5 mM	0.46 mL	2.32 mL	4.64 mL

*The above data is based on the productmolecular weight 431.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

AS703026 (Pimasertib)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions