Chlorprothixene

Catalog No. A10207

Chlorprothixene对下列受体具有强烈的拮抗作用：5-HT2，D1，D2，D3，H1，mACh，α1-肾上腺素。

Technical details

Catalog Num	A10207
M. Wt	315.9
Formula	C18H18ClNS
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	113-59-7
Synonyms	Cloxan, Taractan, Truxal
SMILES	CN(C)CC/C=C\1/C2=CC=CC=C2SC3=C1C=C(C=C3)Cl

Biological Activity

Chlorprothixene对下列受体具有强烈的拮抗作用：5-HT2，D1，D2，D3，H1，mACh，α1-肾上腺素。

Targets

Target	Value
D2receptor	ki: 2.96nM
5-HT6	ki: 3nM
H1receptor	ki: 3.75nM
D3receptor	ki: 4.56nM
5-HT7	ki: 5.6nM
D5receptor	ki: 9nM
5-HT2	ki: 9.4nM
D1receptor	ki: 18nM

Solubility *

In vitro	DMSO	5 mg/mL (15.83 mM)
	Water	Insoluble
	Ethanol	25 mg/mL (79.14 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.66 mL	158.28 mL	316.56 mL
0.5 mM	6.33 mL	31.66 mL	63.31 mL
1 mM	3.17 mL	15.83 mL	31.66 mL
5 mM	0.63 mL	3.17 mL	6.33 mL

*The above data is based on the productmolecular weight 315.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.