Cytarabine

Catalog No. A10265

Cytarabine通过掺入DNA抑制DNA复制（L1210和CEM细胞系中IC50 = 0.04μM）。

Technical details

Catalog Num	A10265
M. Wt	243.2
Formula	C9H13N3O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	147-94-4
Synonyms	Cytosine b-D-arabinofuranoside, cytosine arabinoside, Ara-C
SMILES	C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O

Biological Activity

Cytarabine通过掺入DNA抑制DNA复制（L1210和CEM细胞系中IC50 = 0.04μM）。

Targets

DNA synthesis (CCRF-CEM cells) (CCRF-CEM cells)
16 nM

Solubility *

In vitro (25°C)	DMSO	1 mg/mL (4.11 mM)
	Water	41 mg/mL (168.57 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	41.12 mL	205.59 mL	411.18 mL
0.5 mM	8.22 mL	41.12 mL	82.24 mL
1 mM	4.11 mL	20.56 mL	41.12 mL
5 mM	0.82 mL	4.11 mL	8.22 mL

*The above data is based on the productmolecular weight 243.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.