Dihydroartemisinin

Catalog No. A10310

Dihydroartemisinin是所有青蒿素化合物（青蒿素，青蒿琥酯，青蒿素等）的活性代谢产物，本身也可以用作药物。它是青蒿素的半合成衍生物，被广泛用作制备其他由青蒿素衍生的抗疟药物的中间体。

Product Citations

Xinyu Zhou, .et al. Artemisinin Derivatives Stimulate DR5-Specific TRAIL-Induced Apoptosis by Regulating Wildtype P53, Cancers (Basel), 2020, Sep; 12(9): 2514 PMID: 32899699

Technical details

Catalog Num	A10310
M. Wt	284.35
Formula	C15H24O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	71939-50-9
Synonyms	dihydroqinghaosu,artenimol, DHA
SMILES	[H][C@@]1(C([H])([H])C2([H])[H])[C@]3([C@@]([C@@]4([H])C([H])([H])[H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])OO[C@@]2(C([H])([H])[H])O[C@@]3([H])O[C@@]4([H])O[H]

Biological Activity

Targets

Solubility *

In vitro	DMSO	Warmed: 52 mg/mL (182.87 mM)
	Water	Insoluble
	Ethanol	Warmed: 10 mg/mL (35.16 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.17 mL	175.84 mL	351.68 mL
0.5 mM	7.03 mL	35.17 mL	70.34 mL
1 mM	3.52 mL	17.58 mL	35.17 mL
5 mM	0.7 mL	3.52 mL	7.03 mL

*The above data is based on the productmolecular weight 284.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.