Dofetilide

Catalog No. A10328

Dofetilide是一种III类抗心律不齐药物。Dofetilide的作用是选择性地阻断延迟整流器向外钾电流（Ikr）的快速成分。

Technical details

Catalog Num	A10328
M. Wt	441.56
Formula	C19H27N3O5S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	115256-11-6
Synonyms	UK68798
SMILES	CN(CCC1=CC=C(C=C1)NS(=O)(=O)C)CCOC2=CC=C(C=C2)NS(=O)(=O)C

Biological Activity

Dofetilide是一种III类抗心律不齐药物。Dofetilide的作用是选择性地阻断延迟整流器向外钾电流（Ikr）的快速成分。

Targets

Potassium channel

Solubility *

In vitro	DMSO	Warmed: 82 mg/mL (185.7 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.65 mL	113.23 mL	226.47 mL
0.5 mM	4.53 mL	22.65 mL	45.29 mL
1 mM	2.26 mL	11.32 mL	22.65 mL
5 mM	0.45 mL	2.26 mL	4.53 mL

*The above data is based on the productmolecular weight 441.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.