Epirubicin HCl

Catalog No. A10345

Epirubicin HCl是一种可透过细胞的蒽环类抗肿瘤抗生素。它用于抑制拓扑异构酶II和DNA解旋酶活性。

Technical details

Catalog Num	A10345
M. Wt	580
Formula	C27H30ClNO11
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	56390-09-1
Synonyms	Ellence, Pharmorubicin, Epirubicin Ebewe
SMILES	C[C@H]1[C@@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl

Biological Activity

Epirubicin HCl是一种可透过细胞的蒽环类抗肿瘤抗生素。它用于抑制拓扑异构酶II和DNA解旋酶活性。

Targets

Topoisomerase (Cell-free assay)

Solubility *

In vitro	DMSO	90 mg/mL (155.17 mM)
	Water	Warmed: 90 mg/mL (155.17 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.24 mL	86.21 mL	172.41 mL
0.5 mM	3.45 mL	17.24 mL	34.48 mL
1 mM	1.72 mL	8.62 mL	17.24 mL
5 mM	0.34 mL	1.72 mL	3.45 mL

*The above data is based on the productmolecular weight 580. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.