Evista (Raloxifene HCl)

Catalog No. A10375

Evista (Raloxifene HCl)是一种口服选择性雌激素受体调节剂（SERM），对骨骼具有雌激素作用，对子宫和乳房具有抗雌激素作用。

Product Citations

Renu Sudhakar, .et al. Bazedoxifene, a Postmenopausal Drug, Acts as an Antimalarial and Inhibits Hemozoin Formation, Microbiol Spectr, 2022, Jun 29;10(3) PMID: 35616371

Technical details

Catalog Num	A10375
M. Wt	510
Formula	C28H28ClNO4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	82640-04-8
Synonyms
SMILES	C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl

Biological Activity

Evista (Raloxifene HCl)是一种口服选择性雌激素受体调节剂（SERM），对骨骼具有雌激素作用，对子宫和乳房具有抗雌激素作用。

Targets

ER
5.7 nM

Solubility *

In vitro (25°C)	DMSO	90 mg/mL (176.45 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.61 mL	98.04 mL	196.08 mL
0.5 mM	3.92 mL	19.61 mL	39.22 mL
1 mM	1.96 mL	9.8 mL	19.61 mL
5 mM	0.39 mL	1.96 mL	3.92 mL

*The above data is based on the productmolecular weight 510. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.