Honokiol

Catalog No. A10453

Honokiol是存在于广玉兰的球果、树皮和叶子中的木脂素，在黑色素瘤、肉瘤、骨髓瘤、白血病、膀胱、肺、前列腺、口腔鳞状细胞癌和结肠癌细胞系中显示促凋亡作用。

Technical details

Catalog Num	A10453
M. Wt	266.3
Formula	C18H18O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	35354-74-6
Synonyms	houpa, hnk
SMILES	C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C

Biological Activity

Targets

Akt-phosphorylation	MEK

Solubility *

In vitro (25°C)	DMSO	52 mg/mL (195.24 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.55 mL	187.76 mL	375.52 mL
0.5 mM	7.51 mL	37.55 mL	75.1 mL
1 mM	3.76 mL	18.78 mL	37.55 mL
5 mM	0.75 mL	3.76 mL	7.51 mL

*The above data is based on the productmolecular weight 266.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.