Hydroxyurea

Catalog No. A10459

Hydroxyurea (Cytodrox)是一种抗肿瘤药物，通过抑制核糖核苷二磷酸还原酶来抑制DNA合成。

Technical details

Catalog Num	A10459
M. Wt	76.05
Formula	CH4N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	127-07-1
Synonyms	Hydrea, Biosupressin,Hydroxycarbamide
SMILES	C(=O)(N)NO

Biological Activity

Hydroxyurea (Cytodrox)是一种抗肿瘤药物，通过抑制核糖核苷二磷酸还原酶来抑制DNA合成。

Targets

ribonucleoside diphosphate reductase

Solubility *

In vitro	DMSO	14 mg/mL (184.08 mM)
	Water	14 mg/mL (184.08 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	131.49 mL	657.46 mL	1314.92 mL
0.5 mM	26.3 mL	131.49 mL	262.98 mL
1 mM	13.15 mL	65.75 mL	131.49 mL
5 mM	2.63 mL	13.15 mL	26.3 mL

*The above data is based on the productmolecular weight 76.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.