Irinotecan HCl Trihydrate (Campto)

Catalog No. A10479

Irinotecan (CPT 11)是喜树碱家族的一种化合物，是参与细胞DNA复制和转录的拓扑异构酶1的抑制剂。

Technical details

Catalog Num	A10479
M. Wt	677.2
Formula	C33H38N4O6.HCl.3H2O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	136572-09-3
Synonyms	CPT 11, Camptosar, Campto, Irinotecan
SMILES	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl

Biological Activity

Irinotecan (CPT 11)是喜树碱家族的一种化合物，是参与细胞DNA复制和转录的拓扑异构酶1的抑制剂。

Targets

Topo I

Solubility *

In vitro	DMSO	92 mg/mL (135.86 mM)
	Water	1 mg/mL (1.47 mM)
	Ethanol	6 mg/mL (8.85 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.77 mL	73.83 mL	147.67 mL
0.5 mM	2.95 mL	14.77 mL	29.53 mL
1 mM	1.48 mL	7.38 mL	14.77 mL
5 mM	0.3 mL	1.48 mL	2.95 mL

*The above data is based on the productmolecular weight 677.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.