JNJ-38877605

Catalog No. A10493

JNJ-38877605是一种ATP竞争性的c-Met抑制剂，从而抑制c-Met磷酸化并破坏c-Met信号转导途径。

Technical details

Catalog Num	A10493
M. Wt	377.4
Formula	C19H13F2N7
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	943540-75-8
Synonyms	JNJ38877605
SMILES	CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2

Biological Activity

JNJ-38877605是一种ATP竞争性的c-Met抑制剂，从而抑制c-Met磷酸化并破坏c-Met信号转导途径。

Solubility *

In vitro (25°C)	DMSO	33 mg/mL (87.45 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.5 mL	132.49 mL	264.97 mL
0.5 mM	5.3 mL	26.5 mL	52.99 mL
1 mM	2.65 mL	13.25 mL	26.5 mL
5 mM	0.53 mL	2.65 mL	5.3 mL

*The above data is based on the productmolecular weight 377.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

JNJ-38877605

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions