Leucovorin Calcium

Catalog No. A10524

Calcium Folinate，五水合物为细胞提供四氢叶酸，减少甲氨蝶呤的毒性，但不消除抗肿瘤作用。

Technical details

Catalog Num	A10524
M. Wt	601.58
Formula	C20H21CaN7O7 5H2O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	6035-45-6
Synonyms	Folinic acid calcium salt
SMILES	C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2]

Biological Activity

Calcium Folinate，五水合物为细胞提供四氢叶酸，减少甲氨蝶呤的毒性，但不消除抗肿瘤作用。

Targets

thymidylate synthase

Solubility *

In vitro	DMSO	Insoluble
	Water	Warmed: 11 mg/mL (18.28 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.62 mL	83.11 mL	166.23 mL
0.5 mM	3.32 mL	16.62 mL	33.25 mL
1 mM	1.66 mL	8.31 mL	16.62 mL
5 mM	0.33 mL	1.66 mL	3.32 mL

*The above data is based on the productmolecular weight 601.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.