Methazolastone

Catalog No. A10575

Methazolastone是一种DNA损伤诱导剂。

Product Citations

VJ Herbener, .et al. Considering the Experimental Use of Temozolomide in Glioblastoma Research, Biomedicines, 2020, Jun 4;8(6):E151 PMID: 32512726

Technical details

Catalog Num	A10575
M. Wt	194.15
Formula	C6H6N6O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	85622-93-1
Synonyms	Temozolomide, Temodar, Temodal
SMILES	CN1C(=O)N2C=NC(=C2N=N1)C(=O)N

Biological Activity

Methazolastone是一种DNA损伤诱导剂。

Targets

DNA replication (L-1210, L-1210/BCNU cells)

Solubility *

In vitro (25°C)	DMSO	37 mg/mL (190.57 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	51.51 mL	257.53 mL	515.07 mL
0.5 mM	10.3 mL	51.51 mL	103.01 mL
1 mM	5.15 mL	25.75 mL	51.51 mL
5 mM	1.03 mL	5.15 mL	10.3 mL

*The above data is based on the productmolecular weight 194.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.