Metolazone

Catalog No. A10584

Metolazone和其他噻嗪类利尿剂可抑制氯化钠转运体的功能，并防止钠和氯化物以及水离开管腔进入小管细胞。

Technical details

Catalog Num	A10584
M. Wt	365.8
Formula	C16H16ClN3O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	17560-51-9
Synonyms	Zaroxolyn, Mykrox, Zytanix
SMILES	CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl

Biological Activity

Metolazone和其他噻嗪类利尿剂可抑制氯化钠转运体的功能，并防止钠和氯化物以及水离开管腔进入小管细胞。

Targets

Solubility *

In vitro	DMSO	68 mg/mL (185.87 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (19.13 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.34 mL	136.69 mL	273.37 mL
0.5 mM	5.47 mL	27.34 mL	54.67 mL
1 mM	2.73 mL	13.67 mL	27.34 mL
5 mM	0.55 mL	2.73 mL	5.47 mL

*The above data is based on the productmolecular weight 365.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.