Moxifloxacin HCl

Catalog No. A10609

Moxifloxacin HCl是一种喹诺酮/氟喹诺酮类抗菌剂。

Product Citations

Hiroshi Arakawa, .et al. Possible interaction of quinolone antibiotics with peptide transporter 1 in oral absorption of peptide-mimetic drugs, Biopharm Drug Dispos, 2016, Jan;37(1):39-45 PMID: 26590007
Arisa Higa, .et al. Differing responses of human stem cell-derived cardiomyocytes to arrhythmogenic drugs, determined using impedance measurements, Fundam. Toxicol. Sci, 2016, 3(2): 47-53

Technical details

Catalog Num	A10609
M. Wt	437.9
Formula	C21H24FN3O4.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	186826-86-8
Synonyms	Avelox, Avalox, BAY 12-8039
SMILES	COC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl

Biological Activity

Moxifloxacin HCl是一种喹诺酮/氟喹诺酮类抗菌剂。

Targets

Topoisomerase II	Topoisomerase IV

Solubility *

In vitro (25°C)	DMSO	77 mg/mL (175.84 mM)
	Water	53 mg/mL (121.03 mM)
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.84 mL	114.18 mL	228.36 mL
0.5 mM	4.57 mL	22.84 mL	45.67 mL
1 mM	2.28 mL	11.42 mL	22.84 mL
5 mM	0.46 mL	2.28 mL	4.57 mL

*The above data is based on the productmolecular weight 437.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.