Nepicastat (free base) (SYN-117)

Catalog No. A10637

Nepicastat (free base) (SYN-117)是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。

Technical details

Catalog Num	A10637
M. Wt	295.4
Formula	C14H15F2N3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	173997-05-2
Synonyms	RS-25560-197, SYN117
SMILES	C1CC2=C(C=C(C=C2C[C@H]1N3C(=CNC3=S)CN)F)F

Biological Activity

Nepicastat (free base) (SYN-117)是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。

Solubility *

In vitro (25°C)	DMSO	61 mg/mL (183.83 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.85 mL	169.26 mL	338.52 mL
0.5 mM	6.77 mL	33.85 mL	67.7 mL
1 mM	3.39 mL	16.93 mL	33.85 mL
5 mM	0.68 mL	3.39 mL	6.77 mL

*The above data is based on the productmolecular weight 295.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Nepicastat (free base) (SYN-117)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions