Nobiletin (Hexamethoxyflavone)

Catalog No. A10651

Nobiletin (Hexamethoxyflavone)是一种化学化合物。它是一种O-甲基化黄酮，一种从柑桔皮中分离的类黄酮，就像橘子一样。发现诺比列汀在体外和体内具有抗炎和抗肿瘤的侵袭，增殖和转移。还发现了Nobiletin可能抑制软骨降解。

Product Citations

Yi-Hsin Lo, .et al. Nobiletin Alleviates Ferroptosis-Associated Renal Injury, Inflammation, and Fibrosis in a Unilateral Ureteral Obstruction Mouse Model, Biomedicines, 2022, Mar 3;10(3):595 PMID: 35327397

Technical details

Catalog Num	A10651
M. Wt	402.4
Formula	C21H22O8
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	478-01-3
Synonyms	Hexamethoxyflavone
SMILES	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC

Biological Activity

Targets

MMP	MMP

Solubility *

In vitro	DMSO	70 mg/mL (173.95 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7.45 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.85 mL	124.25 mL	248.51 mL
0.5 mM	4.97 mL	24.85 mL	49.7 mL
1 mM	2.49 mL	12.43 mL	24.85 mL
5 mM	0.5 mL	2.49 mL	4.97 mL

*The above data is based on the productmolecular weight 402.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.