Paliperidone

Catalog No. A10691

Paliperidone (Invega)是一种非典型的抗精神病药。

Product Citations

Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Technical details

Catalog Num	A10691
M. Wt	426.48
Formula	C23H27FN4O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	144598-75-4
Synonyms	Invega, INVEGA Sustenna, 9-hydroxyrisperidone
SMILES	CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F

Biological Activity

Paliperidone (Invega)是一种非典型的抗精神病药。

Targets

Dopamine receptor

Solubility *

In vitro	DMSO	Warmed: 4 mg/mL (9.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.45 mL	117.24 mL	234.48 mL
0.5 mM	4.69 mL	23.45 mL	46.9 mL
1 mM	2.34 mL	11.72 mL	23.45 mL
5 mM	0.47 mL	2.34 mL	4.69 mL

*The above data is based on the productmolecular weight 426.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.