Phloretin (Dihydronaringenin)

Catalog No. A10723

Phloretin (Dihydronaringenin)是通过SGLT1和SGLT2抑制葡萄糖向细胞内的主动转运，尽管这种抑制作用比其糖苷phlorizin弱。

Product Citations

Subramaniam M, .et al. Comparison of Intestinal Glucose Flux and Electrogenic Current Demonstrates Two Absorptive Pathways in Pig and One in Nile Tilapia and Rainbow Trout, Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628

Technical details

Catalog Num	A10723
M. Wt	274.3
Formula	C15H14O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	60-82-2
Synonyms	Dihydronaringenin, Phloretol
SMILES	C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O

Biological Activity

Phloretin (Dihydronaringenin)是通过SGLT1和SGLT2抑制葡萄糖向细胞内的主动转运，尽管这种抑制作用比其糖苷phlorizin弱。

Targets

SGLT1	SGLT2

Solubility *

In vitro	DMSO	46 mg/mL (167.71 mM)
	Water	Insoluble
	Ethanol	46 mg/mL (167.71 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	36.46 mL	182.28 mL	364.56 mL
0.5 mM	7.29 mL	36.46 mL	72.91 mL
1 mM	3.65 mL	18.23 mL	36.46 mL
5 mM	0.73 mL	3.65 mL	7.29 mL

*The above data is based on the productmolecular weight 274.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.