Pramipexole dihydrochloride monohyrate

Catalog No. A10747

Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂，适用于治疗早期帕金森氏病（PD）和不安腿综合征（RLS）。

Technical details

Catalog Num	A10747
M. Wt	302.3
Formula	C10H17N3S.2HCl.H2O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	191217-81-9
Synonyms	Mirapex, Mirapexin, Sifrol
SMILES	CCCN[C@H]1CCC2=C(C1)SC(=N2)N.O.Cl.Cl

Biological Activity

Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂，适用于治疗早期帕金森氏病（PD）和不安腿综合征（RLS）。

Targets

D2S Receptor	D2L Receptor	D3 receptor	D4 receptor

Solubility *

In vitro	DMSO	38 mg/mL (125.72 mM)
	Water	56 mg/mL (185.27 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.08 mL	165.4 mL	330.8 mL
0.5 mM	6.62 mL	33.08 mL	66.16 mL
1 mM	3.31 mL	16.54 mL	33.08 mL
5 mM	0.66 mL	3.31 mL	6.62 mL

*The above data is based on the productmolecular weight 302.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.