Rifampin

Catalog No. A10791

Rifampin是DNA依赖性的RNA聚合酶抑制剂，孕烷X受体（PXR）的原型激活剂。

Product Citations

Meikle V, .et al. A protein complex from human milk enhances the activity of antibiotics and drugs against Mycobacterium tuberculosis, Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480

Technical details

Catalog Num	A10791
M. Wt	882.94
Formula	C43H58N4O12
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	13292-46-1
Synonyms	Rifampicin
SMILES	C[C@H]1/C=C/C=C(\C(=O)NC\2=C(C3=C(C(=C4C(=C3C(=O)/C2=C/NN5CCN(CC5)C)C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C

Biological Activity

Rifampin是DNA依赖性的RNA聚合酶抑制剂，孕烷X受体（PXR）的原型激活剂。

Targets

RNA polymerase

Solubility *

In vitro	DMSO	94 mg/mL (114.22 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.33 mL	56.63 mL	113.26 mL
0.5 mM	2.27 mL	11.33 mL	22.65 mL
1 mM	1.13 mL	5.66 mL	11.33 mL
5 mM	0.23 mL	1.13 mL	2.27 mL

*The above data is based on the productmolecular weight 882.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.