(S)-(+)-Rolipram
Catalog No. A10816
(S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC50 of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells.
| Catalog Num | A10816 |
|---|---|
| M. Wt | 275.34 |
| Formula | C16H21NO3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 85416-73-5 |
| Synonyms | (+)-Rolipram; (S)-Rolipram |
| SMILES | O=C1NC[C@H](C2=CC=C(OC)C(OC3CCCC3)=C2)C1 |
(S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC50 of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.32 mL | 181.59 mL | 363.19 mL |
| 0.5 mM | 7.26 mL | 36.32 mL | 72.64 mL |
| 1 mM | 3.63 mL | 18.16 mL | 36.32 mL |
| 5 mM | 0.73 mL | 3.63 mL | 7.26 mL |
*The above data is based on the productmolecular weight 275.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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