Safinamide Mesylate (FCE28073)

Catalog No. A10818

Safinamide Mesylate是沙芬酰胺的甲磺酸盐，可选择性和可逆地抑制MAO-B，IC50为0.45μM。

Technical details

Catalog Num	A10818
M. Wt	398.5
Formula	C17H19FN2O2.CH4O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	202825-46-5
Synonyms	FCE-28073(R-isomer), PNU-151774E, NW-1015
SMILES	C[C@@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O

Biological Activity

Safinamide Mesylate是沙芬酰胺的甲磺酸盐，可选择性和可逆地抑制MAO-B，IC50为0.45μM。

Targets

MAO-B	MAO-A
98 nM	580 μM

Solubility *

In vitro (25°C)	DMSO	78 mg/mL (195.75 mM)
	Water	78 mg/mL (195.75 mM)
	Ethanol	13 mg/mL (32.62 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.09 mL	125.47 mL	250.94 mL
0.5 mM	5.02 mL	25.09 mL	50.19 mL
1 mM	2.51 mL	12.55 mL	25.09 mL
5 mM	0.5 mL	2.51 mL	5.02 mL

*The above data is based on the productmolecular weight 398.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.