Telaprevir (VX-950)
Catalog No. A10902
Telaprevir (VX-950)被称为蛋白酶抑制剂,可抑制丙型肝炎病毒NS3.4A丝氨酸蛋白酶。
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Catalog Num | A10902 |
---|---|
M. Wt | 679.9 |
Formula | C36H53N7O6 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 402957-28-2 |
Synonyms | VX950, Incivek, Incivo |
SMILES | CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5 |
Telaprevir (VX-950)被称为蛋白酶抑制剂,可抑制丙型肝炎病毒NS3.4A丝氨酸蛋白酶。
Targets
HCV NS3-4A serine protease | ||||
0.35 μM |
In vitro (25°C) | DMSO | 131 mg/mL (192.69 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.71 mL | 73.54 mL | 147.08 mL |
0.5 mM | 2.94 mL | 14.71 mL | 29.42 mL |
1 mM | 1.47 mL | 7.35 mL | 14.71 mL |
5 mM | 0.29 mL | 1.47 mL | 2.94 mL |
*The above data is based on the productmolecular weight 679.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.