Tie2 kinase inhibitor

Catalog No. A10932

Tie2 kinase inhibitor是一种有效的选择性Tie2抑制剂，IC50为0.25μM。

Technical details

Catalog Num	A10932
M. Wt	439.5
Formula	C26H21N3O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	948557-43-5
Synonyms
SMILES	COC1=CC2=C(C=C1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)S(=O)C)C5=CC=NC=C5

Biological Activity

Tie2 kinase inhibitor是一种有效的选择性Tie2抑制剂，IC50为0.25μM。

Targets

Tie-2
0.25 μM

Solubility *

In vitro (25°C)	DMSO	35 mg/mL (79.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% Cremophor EL, 2% N,N-dimethylacetamide	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.75 mL	113.77 mL	227.53 mL
0.5 mM	4.55 mL	22.75 mL	45.51 mL
1 mM	2.28 mL	11.38 mL	22.75 mL
5 mM	0.46 mL	2.28 mL	4.55 mL

*The above data is based on the productmolecular weight 439.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.