Tranilast (SB 252218)

Catalog No. A10942

Tranilast是一种抗过敏药。它减少了成纤维细胞中的胶原蛋白合成，并抑制了神经纤维瘤细胞的生长，还抑制了内皮细胞中白介素6的产生。

Technical details

Catalog Num	A10942
M. Wt	327.3
Formula	C18H17NO5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	53902-12-8
Synonyms	SB252218
SMILES	COC1=C(C=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O)OC

Biological Activity

Tranilast是一种抗过敏药。它减少了成纤维细胞中的胶原蛋白合成，并抑制了神经纤维瘤细胞的生长，还抑制了内皮细胞中白介素6的产生。

Targets

Solubility *

In vitro	DMSO	57 mg/mL (174.14 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.55 mL	152.77 mL	305.53 mL
0.5 mM	6.11 mL	30.55 mL	61.11 mL
1 mM	3.06 mL	15.28 mL	30.55 mL
5 mM	0.61 mL	3.06 mL	6.11 mL

*The above data is based on the productmolecular weight 327.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.