Tretinoin

Catalog No. A10944

Tretinoin 是视黄酸受体的内源性激动剂，RAR-α，RAR-β和RAR-γ受体的IC50值为14 nM。

Technical details

Catalog Num	A10944
M. Wt	300.4
Formula	C20H28O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	302-79-4
Synonyms	Retinoic Acid, ATRA, Vitamin A Acid
SMILES	CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1

Biological Activity

Tretinoin 是视黄酸受体的内源性激动剂，RAR-α，RAR-β和RAR-γ受体的IC50值为14 nM。

Targets

RAR	RXR

Solubility *

In vitro	DMSO	57 mg/mL (189.74 mM)
	Water	Insoluble
	Ethanol	6 mg/mL (19.97 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.29 mL	166.44 mL	332.89 mL
0.5 mM	6.66 mL	33.29 mL	66.58 mL
1 mM	3.33 mL	16.64 mL	33.29 mL
5 mM	0.67 mL	3.33 mL	6.66 mL

*The above data is based on the productmolecular weight 300.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.