AMG 548
Catalog No. A10970
AMG 548是有效的p38α选择性抑制剂。它对其他36种激酶表现出> 1000倍的选择性,并且抑制全血LPS刺激的TNFα。
Catalog Num | A10970 |
---|---|
M. Wt | 461.56 |
Formula | C29H27N5O |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 864249-60-5 |
Synonyms | AMG-548, AMG548 |
SMILES | O=C1N(C)C(NC[C@H](CC2=CC=CC=C2)N)=NC(C3=CC=NC=C3)=C1C4=CC=C5C(C=CC=C5)=C4 |
AMG 548是有效的p38α选择性抑制剂。它对其他36种激酶表现出> 1000倍的选择性,并且抑制全血LPS刺激的TNFα。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.67 mL | 108.33 mL | 216.66 mL |
0.5 mM | 4.33 mL | 21.67 mL | 43.33 mL |
1 mM | 2.17 mL | 10.83 mL | 21.67 mL |
5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
*The above data is based on the productmolecular weight 461.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.