Arry-380 analog

Catalog No. A11027

Arry-380 analog是一种ErbB-2抑制剂,可选择性结合并抑制ErbB-2的磷酸化,从而导致表达ErbB-2的肿瘤细胞的生长抑制和死亡。
Catalog Num A11027
M. Wt 569.9
Formula C29H27N7O4S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 937265-83-3
Synonyms Arry380
SMILES CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5
Arry-380 analog是一种ErbB-2抑制剂,可选择性结合并抑制ErbB-2的磷酸化,从而导致表达ErbB-2的肿瘤细胞的生长抑制和死亡。
In vitro DMSO 90 mg/mL (158 mM)
Water Insoluble
Ethanol 3 mg/mL (5.26 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.55 mL 87.73 mL 175.47 mL
0.5 mM 3.51 mL 17.55 mL 35.09 mL
1 mM 1.75 mL 8.77 mL 17.55 mL
5 mM 0.35 mL 1.75 mL 3.51 mL

*The above data is based on the productmolecular weight 569.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.