Arry-380 analog
Catalog No. A11027
Arry-380 analog是一种ErbB-2抑制剂,可选择性结合并抑制ErbB-2的磷酸化,从而导致表达ErbB-2的肿瘤细胞的生长抑制和死亡。
Catalog Num | A11027 |
---|---|
M. Wt | 569.9 |
Formula | C29H27N7O4S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 937265-83-3 |
Synonyms | Arry380 |
SMILES | CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5 |
Arry-380 analog是一种ErbB-2抑制剂,可选择性结合并抑制ErbB-2的磷酸化,从而导致表达ErbB-2的肿瘤细胞的生长抑制和死亡。
In vitro | DMSO | 90 mg/mL (158 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (5.26 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.55 mL | 87.73 mL | 175.47 mL |
0.5 mM | 3.51 mL | 17.55 mL | 35.09 mL |
1 mM | 1.75 mL | 8.77 mL | 17.55 mL |
5 mM | 0.35 mL | 1.75 mL | 3.51 mL |
*The above data is based on the productmolecular weight 569.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.