Triciribine phosphate (NSC-280594)

Catalog No. A11033

Triciribine phosphate是一种DNA synthesis抑制剂，也抑制PC3细胞系中的Akt和CEM-SS，H9，H9IIIB，U1细胞中的HIV-1，IC50分别为130 nM和20 nM；对PI3K/PDK1没有抑制作用；作用于缺乏腺苷激酶的细胞，活性降低5000

Technical details

Catalog Num	A11033
M. Wt	400.3
Formula	C13H17N6O7P
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	61966-08-3
Synonyms	VQD-002,TCN-P
SMILES	CN1C2=NC=NC3=C2C(=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(O)O)O)O)C(=N1)N

Solubility *

In vitro (25°C)	DMSO	60 mg/mL (187.32 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.98 mL	124.91 mL	249.81 mL
0.5 mM	5 mL	24.98 mL	49.96 mL
1 mM	2.5 mL	12.49 mL	24.98 mL
5 mM	0.5 mL	2.5 mL	5 mL

*The above data is based on the productmolecular weight 400.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Triciribine phosphate (NSC-280594)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions