BMS 599626 (AC480)
Catalog No. A11209
BMS 599626 (AC480)是一种选择性的，高效效的HER1，HER2和HER4酪氨酸激酶抑制剂（IC50分别为22、32和190 nM），具有潜在的抗肿瘤活性。
| Catalog Num | A11209 |
|---|---|
| M. Wt | 567.1 |
| Formula | C27H27FN8O3.HCl |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 873837-23-1 |
| Synonyms | BMS-599626, BMS599626, AC-480 |
| SMILES | CC1=C2C(=NC=NN2C=C1NC(=O)OC[C@@H]3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F.Cl |
BMS 599626 (AC480)是一种选择性的，高效效的HER1，HER2和HER4酪氨酸激酶抑制剂（IC50分别为22、32和190 nM），具有潜在的抗肿瘤活性。
| In vitro (25°C) | DMSO | 104 mg/mL (196.02 mM) | |
| Water | Insoluble | ||
| Ethanol | 18 mg/mL (33.92 mM) | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.63 mL | 88.17 mL | 176.34 mL |
| 0.5 mM | 3.53 mL | 17.63 mL | 35.27 mL |
| 1 mM | 1.76 mL | 8.82 mL | 17.63 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.53 mL |
*The above data is based on the productmolecular weight 567.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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